The role of histone modifications and DNA methylation in renal cell carcinoma development
| Autor: | Lilia R Kutlyeva, Elsa K Khusnutdinova, Irina R Gilayzova, Rita I Khusainova |
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| Rok vydání: | 2012 |
| Předmět: |
модификации гистонов
lcsh:QH426-470 Ecology biology эпигенетические факторы EZH2 метилирование днк гены-супрессоры опухолевого роста Biochemistry lcsh:Genetics Histone Histone methyltransferase Histone H2A DNA methylation Genetics biology.protein Cancer research Epigenetics Cancer epigenetics рак почки Genetics (clinical) Ecology Evolution Behavior and Systematics Epigenomics |
| Zdroj: | Экологическая генетика, Vol 10, Iss 3, Pp 59-76 (2012) |
| ISSN: | 2411-9202 1811-0932 |
| DOI: | 10.17816/ecogen10359-76 |
| Popis: | Epigenetic mechanisms of gene regulation play a key role in carcinogenesis. This review will focus on the recent advances of epigenetic investigations in the development of human cancer. The role of histone modifications, genomic imprinting and DNA methylation in renal cell carcinoma development and progression will be considered. |
| Databáze: | OpenAIRE |
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