Myoglobinuric renal failure due to long-standing lovastatin therapy in a patient with pre-existing chronic renal insufficiency
| Autor: | Jan Zazgornik, Othmar Janko, Stuby U, Georg Biesenbach |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Hypercholesterolemia urologic and male genital diseases Rhabdomyolysis Nephrotoxicity medicine Humans Chronic renal insufficiency In patient Lovastatin Enzyme Inhibitors Aged Transplantation business.industry Anticholesteremic Agents Myoglobinuria Hmgcoa reductase Acute Kidney Injury medicine.disease Surgery Nephrology Kidney Failure Chronic Hydroxymethylglutaryl-CoA Reductase Inhibitors Complication business medicine.drug |
| Zdroj: | Nephrology Dialysis Transplantation. 11:2059-2060 |
| ISSN: | 1460-2385 0931-0509 |
| DOI: | 10.1093/oxfordjournals.ndt.a027097 |
| Popis: | Atraumatic rhabdomyolysis with consecutive acute myoglobinuric renal failure due to lipid-lowering drugs is a rare complication. In earlier years fibrateassociated rhabdomyolysis was observed more commonly in patients with renal insufficiency [1]. There are relatively rare case reports concerning rhabdomyolysis and renal damage due to therapy with HMGCoA reductase inhibitors; in most of the cases, however, patients had had renal insufficiency or had received other nephrotoxic drugs [2]. We describe a case of lovastatin-induced myoglobinuric renal failure after 4 years of lovastatin therapy in a patient with pre-existing renal insufficiency. |
| Databáze: | OpenAIRE |
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