Acid, silver, and solvent-free gold-catalyzed hydrophenoxylation of internal alkynes
| Autor: | Kevin J. Garcia, Marcia E. Richard, Robert A. Stockland, Daniel Vincent Fraccica, Peter M. Findeis, Victoria L. Resh, Rosa M. Ciccarelli, Erica J. Miller, Aakash Shah, Erin C. Holahan |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
silver-free
010402 general chemistry solvent-free 01 natural sciences Full Research Paper Catalysis lcsh:QD241-441 Silver salts chemistry.chemical_compound lcsh:Organic chemistry Organic chemistry Phenols hydrophenoxylation lcsh:Science acid-free Solvent free catalysis 010405 organic chemistry organic chemicals Single component Organic Chemistry single component gold gold catalysis 0104 chemical sciences Chemistry chemistry lcsh:Q Carbene |
| Zdroj: | Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 2002-2008 (2013) Beilstein Journal of Organic Chemistry |
| ISSN: | 1860-5397 |
| DOI: | 10.3762/bjoc.9.235 |
| Popis: | A range of arylgold compounds have been synthesized and investigated as single-component catalysts for the hydrophenoxylation of unactivated internal alkynes. Both carbene and phosphine-ligated compounds were screened as part of this work, and the most efficient catalysts contained either JohnPhos or IPr/SIPr. Phenols bearing either electron-withdrawing or electron-donating groups were efficiently added using these catalysts. No silver salts, acids, or solvents were needed for the catalysis, and either microwave or conventional heating afforded moderate to excellent yields of the vinyl ethers. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|