Spondylodiscitis complicating infective endocarditis
| Autor: | Mesut Gun, Didier Raoult, Quentin Delpierre, Fanny Peugnet, Serge Cammilleri, Jean-Paul Casalta, Michel Drancourt, Antonello D'Andrea, Basile Mouhat, Francesco Santelli, Christophe Tribouilloy, Florent Arregle, Laurence Camoin-Jau, Hélène Martel, Yohann Bohbot, Alberto Riberi, Audrey Lieu, Laetitia Tessonnier, Andreina Carbone, Frédérique Gouriet, M. Philip, Frederic Collart, Gilbert Habib, Eric Guedj |
|---|---|
| Přispěvatelé: | Carbone, A., Lieu, A., Mouhat, B., Santelli, F., Philip, M., Bohbot, Y., Tessonnier, L., Peugnet, F., D'Andrea, A., Cammilleri, S., Delpierre, Q., Gouriet, F., Camoin-Jau, L., Gun, M., Casalta, J. -P., Riberi, A., Collart, F., Martel, H., Arregle, F., Guedj, E., Raoult, D., Drancourt, M., Tribouilloy, C., Habib, G., Hôpital de la Timone [CHU - APHM] (TIMONE), Université de Picardie Jules Verne (UPJV), Département de Médecine Nucléaire [AP-HM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE)- Hôpital Nord [CHU - APHM], Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Assistance Publique - Hôpitaux de Marseille (APHM), Service Central de Biophysique et de Médecine Nucléaire, Service de Cardiologie [Amiens], CHU Amiens-Picardie, Service de cardiologie, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie |
| Rok vydání: | 2019 |
| Předmět: |
Spondylodiscitis
Male medicine.medical_specialty Prognostic variable Discitis cardiac imaging and diagnostics 030204 cardiovascular system & hematology Multimodal Imaging endocarditis 03 medical and health sciences 0302 clinical medicine [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Internal medicine Positron Emission Tomography Computed Tomography medicine Endocarditis Humans [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology In patient Prospective Studies ComputingMilieux_MISCELLANEOUS Aged Aged 80 and over [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases cardiac imaging and diagnostic business.industry Mean age Middle Aged medicine.disease Prognosis [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology 3. Good health Infective endocarditis [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Pyogenic spondylodiscitis Female Cardiology and Cardiovascular Medicine Complication business 030217 neurology & neurosurgery |
| Zdroj: | Heart Heart, BMJ Publishing Group, 2020, pp.heartjnl-2019-316492. ⟨10.1136/heartjnl-2019-316492⟩ Heart, 2020, pp.heartjnl-2019-316492. ⟨10.1136/heartjnl-2019-316492⟩ |
| ISSN: | 1468-201X 1355-6037 |
| Popis: | ObjectiveThe primary objective was to assess the characteristics and prognosis of pyogenic spondylodiscitis (PS) in patients with infective endocarditis (IE). The secondary objectives were to assess the factors associated with occurrence of PS.MethodsProspective case–control bi-centre study of 1755 patients with definite IE with (n=150) or without (n=1605) PS. Clinical, microbiological and prognostic variables were recorded.ResultsPatients with PS were older (mean age 69.7±18 vs 66.2±14; p=0.004) and had more arterial hypertension (48% vs 34.5%; pStreptococcus gallolyticus were more frequent (24% vs 12% and 24% vs 11%; p18F-FDG PET/CT in 56 patients. In-hospital (16% vs 13.5%, p=0.38) and 1-year (21% vs 22%, p=0.82) mortalities did not differ between patients with or without PS.ConclusionsPS is a frequent complication of IE (8.5% of IE), is observed in older hypertensive patients with enterococcal or S. gallolyticus IE, and has a similar prognosis than other forms of IE. Since PS is associated with specific management, multimodality imaging including MRI, CT and PET/CT should be used for early diagnosis of this complication of endocarditis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|