Value of health-related quality of life to predict disability course in multiple sclerosis
| Autor: | Luc Vleugels, Emma H. Collette, B.M.J. Uitdehaag, M. A.J. Visschedijk, Martin Klein, Chris H. Polman, L.E.M.A. Pfennings, E.L.J. Hoogervorst, E. van der Ploeg, H M van der Ploeg |
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| Přispěvatelé: | Neurology, Amsterdam Neuroscience - Neuroinfection & -inflammation, CCA - Imaging and biomarkers, Medical psychology, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, CCA - Cancer Treatment and quality of life, NCA - Neurobiology of mental health, VU University medical center |
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Gerontology
Adult Male medicine.medical_specialty Multivariate analysis Multiple Sclerosis Patients Logistic regression Severity of Illness Index Disability Evaluation Quality of life (healthcare) Belgium Surveys and Questionnaires Severity of illness medicine Humans Depression (differential diagnoses) Aged Netherlands Expanded Disability Status Scale business.industry Multiple sclerosis Middle Aged medicine.disease Logistic Models Multivariate Analysis Physical therapy Disease Progression Quality of Life Female Neurology (clinical) business Value (mathematics) Follow-Up Studies Forecasting |
| Zdroj: | Visschedijk, M A J, Uitdehaag, B M J, Klein, M, Van Der Ploeg, E, Collette, E H, Vleugels, L, Pfennings, L E M A, Hoogervorst, E L J, Van Der Ploeg, H M & Polman, C H 2004, ' Value of health-related quality of life to predict disability course in multiple sclerosis ', Neurology, vol. 63, no. 11, pp. 2046-2050 . https://doi.org/10.1212/01.WNL.0000145769.51420.ED Neurology, 63(11), 2046-2050. Lippincott Williams and Wilkins Scopus-Elsevier |
| ISSN: | 0028-3878 |
| Popis: | Objective: To determine the value of health-related quality of life (HRQoL) to predict change in disability status in patients with multiple sclerosis (MS). Methods: Over a 5-year period, data were collected on HRQoL (Medical Outcomes Study Short Form-36 Health Survey) and disability status (Expanded Disability Status Scale) from a heterogeneous group of 81 Dutch-speaking patients with MS. Results: Multivariate logistic regression analysis showed that HRQoL in the domains of Physical Functioning and Role-Physical Functioning is a significant predictor of change in disability status. Conclusions: A patient's subjectively perceived health-related quality of life may not be only a clinically and psychosocially meaningful outcome per se but may also be a predictor of objective outcomes such as change in disability status over a substantial period of time. |
| Databáze: | OpenAIRE |
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