Retinal function in patients with serpiginous choroiditis: a microperimetry study
Autor: | Vuga Ana Grgic, Patrik Sportiello, Edoardo Midena, Enrica Convento, Elisabetta Pilotto, Stela Vujosevic, Antonio G. Secchi |
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Rok vydání: | 2010 |
Předmět: |
Indocyanine Green
Male medicine.medical_specialty Choroiditis Visual acuity genetic structures Posterior pole Visual Acuity Fixation Ocular Retina Cellular and Molecular Neuroscience chemistry.chemical_compound Optics Ophthalmology medicine Humans Fluorescein Angiography Coloring Agents Scotoma Serpiginous choroiditis medicine.diagnostic_test business.industry Blind spot Retinal Middle Aged medicine.disease Fluorescein angiography eye diseases Sensory Systems chemistry Fixation (visual) Visual Field Tests sense organs medicine.symptom business Microperimetry |
Zdroj: | Graefe's Archive for Clinical and Experimental Ophthalmology. 248:1331-1337 |
ISSN: | 1435-702X 0721-832X |
Popis: | To investigate fixation pattern and retinal sensitivity in patients with serpiginous choroiditis (SC). Twenty-eight eyes (14 patients) with SC were evaluated. Best-corrected visual acuity, color fundus photography, fundus autofluorescence, and fluorescein and indocyanine green angiography were performed. Microperimetry was used to assess fixation pattern and retinal sensitivity. Of 28 eyes, 16 (57%) had central, one (4%) poor central, and 11 (39%) eccentric fixation; and 18 (64%) had stable, four (14%) relatively unstable, and six (21%) unstable fixation. In patients with posterior pole symmetrically involved in both eyes, the better eye had stable and central fixation in all cases. Atrophic lesions were characterized by a dense scotoma in all cases, with a relative scotoma at their margins in ten eyes (38%). In two cases of active disease, a dense scotoma correlated to an active lesion could be detected. A relative scotoma was documented in areas not involved by the disease at the posterior pole in eight eyes (28%), and in the peripapillary area in 11 eyes (39%). Quantification of retinal sensitivity and fixation pattern by microperimetry offers new data about the impact of visual impairment in patients with SC. A reduction of retinal sensitivity in an apparently healthy area suggests a wider functional involvement of the retina, undetectable by morphologic evaluation alone. |
Databáze: | OpenAIRE |
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