The impact of radiation treatment planning technique on unplanned hospital admissions
| Autor: | Nathan E. Goldstein, Erin Moshier, Juan P. Wisnivesky, Doran Ricks, Madhu Mazumdar, Sanders Chang, Kavita V. Dharmarajan, Meng Ru |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty Reduced risk Hematologic cancer Palliative Radiation Therapy business.industry lcsh:R895-920 Hazard ratio Palliative Care Competing risks lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Tertiary care lcsh:RC254-282 Confidence interval 3. Good health 03 medical and health sciences 0302 clinical medicine Oncology 030220 oncology & carcinogenesis Internal medicine medicine Radiology Nuclear Medicine and imaging 030212 general & internal medicine Radiation treatment planning business |
| Zdroj: | Advances in Radiation Oncology, Vol 3, Iss 4, Pp 647-654 (2018) Advances in Radiation Oncology |
| ISSN: | 2452-1094 |
| Popis: | Purpose Treatment burdens and toxicities related to palliative radiation therapy (RT) may lead to unplanned hospital admissions (UHAs). The likelihood for these toxicities may be related to treatment technique. We compared rates of UHA between patients receiving nonconformal (2-dimensional) and conformal (3-dimensional or higher) radiation treatments to bone metastases involving the vertebral column. Methods and materials We retrospectively analyzed patients treated with RT for bone metastases at a single tertiary care center between 2010 and 2017. We compared rates of RT-related UHA within 90 days of receiving radiation using Cox competing risk regression models. Results We identified 326 patients with bone metastases involving the vertebral column, 139 of whom received radiation by nonconformal technique and 187 by conformal technique. On multivariable analysis, conformal techniques were associated with a reduced risk of 90-day UHA (hazard ratio [HR]: 0.35; 95% confidence interval [CI], 0.14-0.88). Other significant factors include hematologic cancer (HR: 0.17; 95% CI, 0.03-0.82) and baseline Eastern Cooperative Oncology Group score ≥2 (HR: 3.02; 95% CI, 1.05-8.69). Conclusions The utilization of conformal (non-2-dimensional) radiation treatment plans may help reduce treatment-related toxicities and consequently UHAs after palliation of bone metastases. |
| Databáze: | OpenAIRE |
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