Dramatic post-cardiotomy outcome, due to severe anaphylactic reaction to protamine

Autor: X Orrit, Aristotelis Panos, Afksendiyos Kalangos, Catherine Chevalley
Rok vydání: 2003
Předmět:
Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Protamine sulfate
medicine.medical_treatment
Heparin Antagonists/adverse effects
Postoperative Complications/chemically induced
Aortic Aneurysm/surgery
law.invention
Blood Vessel Prosthesis Implantation
Fatal Outcome
Postoperative Complications
law
medicine.artery
Ascending aorta
Cardiopulmonary bypass
medicine
Humans
Protamines
Adverse effect
Anaphylaxis
Protamines/adverse effects
Aorta
Cardiopulmonary Bypass
ddc:617
biology
business.industry
Heparin Antagonists
General Medicine
Middle Aged
medicine.disease
Protamine
Aortic Aneurysm
Surgery
Shock (circulatory)
Anesthesia
Aorta/surgery
biology.protein
Anaphylaxis/chemically induced
Heart-Assist Devices
medicine.symptom
Cardiology and Cardiovascular Medicine
Cardiotomy
business
medicine.drug
Zdroj: European Journal of Cardio-Thoracic Surgery, Vol. 24, No 2 (2003) pp. 325-7
ISSN: 1010-7940
DOI: 10.1016/s1010-7940(03)00252-5
Popis: Immunologic reactions to protamine sulfate during cardiac surgery are very rare. The frequency and outcome of such adverse reactions is unclear. We report a case of lethal anaphylactic reaction to protamine that occurred in a non-diabetic patient following the uneventful replacement of the ascending aorta. We also briefly review the mechanisms of this adverse reaction and emit some considerations on the management of this situation.
Databáze: OpenAIRE
Externí odkaz: