Closing Clostridium botulinum Group III Genomes Using Long-Read Sequencing
| Autor: | Christelle Mazuet, Luca Bano, Tommi Mäklin, Yağmur Derman, Miia Lindström, Cedric Woudstra, Hanna Skarin, Antti Honkela |
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| Přispěvatelé: | Food Hygiene and Environmental Health, Department of Mathematics and Statistics, Miia Lindström / Principal Investigator, Probabilistic Mechanistic Models for Genomics research group / Antti Honkela, Department of Computer Science |
| Rok vydání: | 2021 |
| Předmět: |
11832 Microbiology and virology
0303 health sciences biology 030306 microbiology Genome Sequences PHAGE 113 Computer and information sciences medicine.disease_cause medicine.disease biology.organism_classification Genome Microbiology 03 medical and health sciences Immunology and Microbiology (miscellaneous) Genetics medicine Clostridium botulinum Neurotoxin Botulism Molecular Biology Bacteria 030304 developmental biology |
| Zdroj: | Microbiology Resource Announcements |
| ISSN: | 2576-098X |
| DOI: | 10.1128/mra.01364-20 |
| Popis: | Clostridium botulinum group III is the anaerobic Gram-positive bacteria producing the deadly neurotoxin responsible for animal botulism. Here, we used long-read sequencing to produce four complete genomes from Clostridium botulinum group III neurotoxin types C, D, C/D, and D/C. The protocol to obtain high-molecular-weight DNA from C. botulinum group III is described. |
| Databáze: | OpenAIRE |
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