Clinical observations on the time factor in interstitial radiotherapy using Iridium-192
| Autor: | Baillet F, B. Pierquin, C. H. Paine, D. Chassagne |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Male
medicine.medical_specialty Skin Neoplasms Time Factors Necrosis Brachytherapy Biological effect Interstitial radiotherapy medicine Humans Anterior tongue Dosimetry Radiology Nuclear Medicine and imaging Penile Neoplasms Floor of mouth business.industry Radiotherapy Dosage General Medicine Iridium Radioisotopes Surgery Time factor medicine.anatomical_structure Head and Neck Neoplasms Carcinoma Squamous Cell Radiology Neoplasm Recurrence Local medicine.symptom business Penis Half-Life |
| Zdroj: | Clinical Radiology. 24:506-509 |
| ISSN: | 0009-9260 |
| DOI: | 10.1016/s0009-9260(73)80166-7 |
| Popis: | The different linear activities of Iridium-192 wires which we have used for implantation, together with our system of dosimetry, have resulted in a 3-fold variation in the total time over which our standard tumour dose has been delivered to the 263 cases here assessed, which have been treated exclusively by interstitial therapy. Necrosis and recurrence rates have been related to overall treatment time for squamous carcinomas of the skin, lip, penis, anterior tongue and floor of the mouth. It is found, though without enough cases for statistical proof, that overall treatment time may vary from 3 to 9 days without apparent effect upon either necrosis rate or recurrence rate. We conclude that adjustments to overall time which have sometimes been suggested to compensate for such a supposed biological effect are unnecessary, and may even sometimes result in under-dosage of the tumour. |
| Databáze: | OpenAIRE |
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