Correlation between early brain natriuretic peptide level and mortality in cancer patients with septic shock
| Autor: | Chunyi Hao, Ren-Xiong Chen, Jiahua Leng, Hongzhi Wang, Yong Yang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Gastroenterology Procalcitonin law.invention 03 medical and health sciences 0302 clinical medicine law Neoplasms Internal medicine Natriuretic Peptide Brain medicine Humans 030212 general & internal medicine Risk factor Retrospective Studies Advanced and Specialized Nursing Univariate analysis Receiver operating characteristic Septic shock business.industry Cancer 030208 emergency & critical care medicine Prognosis medicine.disease Brain natriuretic peptide Shock Septic Intensive care unit Anesthesiology and Pain Medicine business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Annals of Palliative Medicine. 10:4214-4219 |
| ISSN: | 2224-5839 2224-5820 |
| Popis: | BACKGROUND This study aimed to examine the correlation between early brain natriuretic peptide (BNP) levels and mortality in cancer patients with septic shock. METHODS A retrospective analysis of 159 cancer patients with septic shock admitted to the intensive care unit (ICU) from Dec. 2012 to Dec. 2019 was performed. BNP levels and other variables, including blood lactate (Lac), procalcitonin (PCT), white blood cell (WBC) counts, acute physiology and chronic health status system II scores (APACHE-II scores) were collected within 24 hours after ICU admission. According to 28-day mortality, patients were divided into a death group (60 cases) and a survival group (99 cases). All variables were compared by univariate analysis, and then a multiple logistic regression analysis was performed on the variables that showed significant differences. Receiver operating characteristic curve (ROC curve) analysis was used to evaluate the predictive value of BNP on mortality in cancer patients with septic shock. RESULTS BNP, APACHE-II score, Lac, and PCT in the death group were significantly higher than those in the survival group (P |
| Databáze: | OpenAIRE |
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