Biologically active quinoline and quinazoline alkaloids part II

Autor:	Xiao-Fei Shang, Susan L. Morris-Natschke, Guan-Zhou Yang, Ying-Qian Liu, Xiao Guo, Xiao-Shan Xu, Masuo Goto, Jun-Cai Li, Ji-Yu Zhang, Kuo-Hsiung Lee
Rok vydání:	2018
Předmět:	Pharmacology 010405 organic chemistry Anti-Inflammatory Agents Protective Agents 010402 general chemistry 01 natural sciences Antioxidants Article 0104 chemical sciences Alkaloids Drug Discovery Quinazolines Quinolines Humans Molecular Medicine
Zdroj:	Medicinal Research Reviews. 38:1614-1660
ISSN:	0198-6325 2009-2016
Popis:	To follow-up on our prior Part I review, this Part II review summarizes and provides updated literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009-2016, together with the biological activity and the mechanisms of action of these classes of natural products. Over 200 molecules with a broad range of biological activities, including antitumor, antiparasitic and insecticidal, antibacterial and antifungal, cardioprotective, antiviral, anti-inflammatory, hepatoprotective, antioxidant, anti-asthma, antitussive, and other activities, are discussed. This survey should provide new clues or possibilities for the discovery of new and better drugs from the original naturally occurring quinoline and quinazoline alkaloids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1f3c618f6e241df22af52f98baac18 https://doi.org/10.1002/med.21492 Zobrazit plný text záznamu Plný text