The impact of gender on treatment effectiveness of body psychotherapy for negative symptoms of schizophrenia
| Autor: | Ulrich Reininghaus, Richard P. Bentall, Til Wykes, Stefan Priebe, Stavros Orfanos, Mark Savill |
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| Přispěvatelé: | RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Arts therapies THERAPY CLINICAL-ASSESSMENT INTERVIEW law.invention 0302 clinical medicine Randomized controlled trial law Secondary analysis Men Middle Aged RANDOMIZED CONTROLLED-TRIAL Psychiatry and Mental health Treatment Outcome Schizophrenia Subgroup analysis Female Schizophrenic Psychology Psychology Clinical psychology Adult EXPRESSION medicine.medical_specialty Psychosis SEX-DIFFERENCES Adolescent DISORDERS Affect (psychology) Article VALIDATION Body psychotherapy 03 medical and health sciences Young Adult Sex Factors medicine Humans Women Psychiatry Biological Psychiatry Psychological treatment Aged 1ST-EPISODE medicine.disease 030227 psychiatry Psychotherapy EXPERIENCE CAINS 030217 neurology & neurosurgery |
| Zdroj: | Psychiatry Research, 247, 73-78. Elsevier Ireland Ltd Savill, M, Orfanos, S, Bentall, R, Reininghaus, U, Wykes, T & Priebe, S 2017, ' The impact of gender on treatment effectiveness of body psychotherapy for negative symptoms of schizophrenia : A secondary analysis of the NESS trial data ', Psychiatry Research, vol. 247, pp. 73-78 . https://doi.org/10.1016/j.psychres.2016.11.020 |
| ISSN: | 0165-1781 |
| DOI: | 10.1016/j.psychres.2016.11.020 |
| Popis: | Despite promising findings from small-scale studies suggesting that body psychotherapy may be an effective treatment for negative symptoms, these results were not replicated in a recent multisite trial. In this trial a far smaller proportion of women were recruited relative to earlier studies, which may be an issue given the gender mix of the sample evaluated has been found to affect trial outcomes in schizophrenia. Using data from our multisite trial, the interaction between gender and treatment allocation as a predictor of outcomes was examined in 275 participants (72 women and 203 men) randomised to either a body psychotherapy or Pilates group. Negative symptoms were found to significantly reduce in women randomised to the body psychotherapy condition in comparison to Pilates, while no such effect was detected in men. Consistent with the smaller trials, this improvement was found to relate predominantly to expressive deficits. These findings suggest that body psychotherapy may be an effective treatment for negative symptoms in women. These findings emphasise the importance of sample characteristics in determining trial outcome in psychological treatment studies. |
| Databáze: | OpenAIRE |
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