Elastic stent recoil in coronary total occlusions
| Autor: | Jeroen Wilschut, Roberto Diletti, Joost Daemen, Paola Scarparo, Wijnand K den Dekker, Nicolas M. Van Mieghem, Riccardo Improta, Felix Zijlstra, Quinten Wolff |
|---|---|
| Přispěvatelé: | Cardiology, Public Health |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Polymers
medicine.medical_treatment Coronary Artery Disease 030204 cardiovascular system & hematology Prosthesis Design Elastic recoil 03 medical and health sciences 0302 clinical medicine Percutaneous Coronary Intervention Restenosis Absorbable Implants medicine Humans Radiology Nuclear Medicine and imaging 030212 general & internal medicine Everolimus Sirolimus business.industry Stent Percutaneous coronary intervention Cardiovascular Agents Drug-Eluting Stents General Medicine medicine.disease Thrombosis Confidence interval Treatment Outcome Drug-eluting stent Cardiology and Cardiovascular Medicine business Nuclear medicine medicine.drug |
| Zdroj: | Catheterization and Cardiovascular Interventions, 99(1), 88-97. Wiley-Liss Inc. |
| ISSN: | 1522-726X 1522-1946 |
| Popis: | Objectives To compare stent recoil (SR) of the thin-strut durable-polymer Zotarolimus-eluting stent (dp-ZES) and the ultrathin-strut bioabsorbable-polymer Sirolimus-eluting stent (bp-SES) in chronic total occlusions (CTOs) and to investigate the predictors of high SR in CTOs. Background Newer ultrathin drug eluting stent might be associated with lower radial force and higher elastic recoil due to the thinner strut design, possibly impacting on the rate of in-stent restenosis and thrombosis. Methods Between January 2017 and November 2019, consecutive patients with CTOs undergoing percutaneous coronary intervention were evaluated. Only patients treated with dp-ZES or bp-SES were included and stratified accordingly. Quantitative coronary angiography analysis was used to assess absolute SR, relative SR, absolute focal SR, relative focal SR, high absolute, and high relative focal SR. Results A total of 128 lesions (67 treated with dp-ZES and 61 with bp-SES) in 123 patients were analyzed. Between bp-SES and dp-ZES no differences were found in absolute SR (p = .188), relative SR (p = .138), absolute focal SR (p = .069), and relative focal SR (p = .064). High absolute and high relative focal SR occurred more frequently in bp-SES than in dp-ZES (p = .004 and p = .015). Bp-SES was a predictor of high absolute focal SR (Odds ratio [OR] 3.29, 95% confidence interval [CI] 1.50-7.22, p = .003]. High-pressure postdilation and bp-SES were predictors of high relative focal SR (OR 2.22, 95% CI 1.01-4.86, p = .047; OR 2.74, 95% CI 1.24-6.02, p = .012, respectively). Conclusions Both stents showed an overall low SR. However, ultra-thin strut bp-SES was a predictor of high absolute and high relative focal SR. |
| Databáze: | OpenAIRE |
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