Anaemia in the first but not in the second or third trimester is a risk factor for low birth weight
Autor: | Katja Hakkarainen, Seppo Heinonen, Henna Hämäläinen |
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Rok vydání: | 2003 |
Předmět: |
Adult
medicine.medical_specialty Adolescent Birth weight Pregnancy Trimester Third Prenatal care Critical Care and Intensive Care Medicine Third trimester Hemoglobins Pregnancy Risk Factors hemic and lymphatic diseases Medicine Humans Risk factor Finland Retrospective Studies Nutrition and Dietetics business.industry Obstetrics Confounding Infant Newborn Pregnancy Outcome Gestational age Anemia Infant Low Birth Weight medicine.disease Pregnancy Complications Low birth weight Pregnancy Trimester First Pregnancy Trimester Second Female medicine.symptom business Infant Premature |
Zdroj: | Clinical nutrition (Edinburgh, Scotland). 22(3) |
ISSN: | 0261-5614 |
Popis: | Objective: To assess pregnancy outcome in women with anaemia during pregnancy. Methods: The study design involved a retrospective chart review of all women registering for prenatal care in the area of Kuopio University Hospital between 1990 and 2000. A haemoglobin concentration below 100 g/l was used as a cutoff for anaemia and affected women (N=597) were stratified by the trimester at which anaemia was diagnosed. Multiple regression analysis was used to compare obstetric outcomes in the study groups and in non-anaemic women (N=22,202). Results: The frequency of anaemia was 2.6%, with 0.3% occurring in the first trimester. After controlling for confounding factors, anaemia detected in the first trimester was associated with low-birth-weight infants (OR=3.14, 95% CI: 1.35–7.28) whereas the mid- and third-trimester anaemia groups showed no significantly different outcomes when compared with the non-anaemic women. First trimester anaemia was not significantly associated with small birth weight for gestational age (OR=0.98, 95% CI: 0.41–2.17) or with premature delivery Conclusions: Maternal anaemia detected in the first trimester is associated with low birth weight. |
Databáze: | OpenAIRE |
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