Robot-assisted gait training is not superior to intensive overground walking in multiple sclerosis with severe disability (the RAGTIME study): A randomized controlled trial
Autor: | Elisa Maietti, Nino Basaglia, Sofia Straudi, Nicola Lamberti, Carlotta Martinuzzi, Fabio Manfredini |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male 030506 rehabilitation medicine.medical_specialty medicine.medical_treatment LS5_11 Walking law.invention NO rehabilitation 03 medical and health sciences 0302 clinical medicine Gait (human) Physical medicine and rehabilitation Gait training Randomized controlled trial law Outcome Assessment Health Care medicine Humans Single-Blind Method Severe disability Gait Disorders Neurologic Progressive multiple sclerosis Mobility Rehabilitation training exercise business.industry Multiple sclerosis Overground walking Robotics Middle Aged Multiple Sclerosis Chronic Progressive medicine.disease robot-assisted gait training Exercise Therapy Walking Speed motor recovery progressive multiple sclerosis Neurology Female Neurology (clinical) 0305 other medical science business Mobility motor recovery progressive multiple sclerosis rehabilitation robot-assisted gait training exercise training 030217 neurology & neurosurgery Follow-Up Studies |
Zdroj: | Multiple sclerosis (Houndmills, Basingstoke, England). 26(6) |
ISSN: | 1477-0970 |
Popis: | Background:Rehabilitation may attenuate the impact on mobility of patients with progressive multiple sclerosis (MS) and severe gait disabilities.Objective:In this randomized controlled trial, we compared robot-assisted gait training (RAGT) with conventional therapy (CT) in terms of gait speed, mobility, balance, fatigue and quality of life (QoL).Methods:Seventy-two patients with MS (expanded disability status scale score 6.0–7.0) were randomized to receive 12 training sessions over a 4-week period of RAGT ( n = 36) or overground walking therapy ( n = 36). The primary outcome was gait speed, assessed by the timed 25-foot walk test. Secondary outcome measures were walking endurance, balance, depression, fatigue and QoL. Tests were performed at baseline, intermediate, at the end of treatment and at a 3-month follow-up.Results:Sixty-six patients completed the treatments. At the end of treatment with respect to baseline, both groups significantly improved gait speed ( p Conclusions:RAGT was not superior to CT in improving gait speed in patients with progressive MS and severe gait disabilities where a positive, even transitory, effect of rehabilitation was observed. |
Databáze: | OpenAIRE |
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