Urodynamic Outcomes After Aquablation
| Autor: | Peter J. Gilling, Marie Adrianne Pimentel, Omid Yassaie |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Ablation Techniques
Male medicine.medical_specialty Urology medicine.medical_treatment Prostatic Hyperplasia 030232 urology & nephrology urologic and male genital diseases law.invention 03 medical and health sciences Bladder outlet obstruction 0302 clinical medicine Double-Blind Method Randomized controlled trial law Prostate medicine Humans Endoscopic resection Prospective Studies Prospective cohort study Aged Transurethral resection of the prostate Aged 80 and over Prostatectomy business.industry Transurethral Resection of Prostate Water Middle Aged Urinary Bladder Neck Obstruction Urodynamics Treatment Outcome medicine.anatomical_structure Multicenter study 030220 oncology & carcinogenesis Ablation Therapy business |
| Zdroj: | Urology. 126:165-170 |
| ISSN: | 0090-4295 |
| DOI: | 10.1016/j.urology.2019.01.020 |
| Popis: | To compare urodynamic outcomes between Aquablation vs transurethral resection of the prostate (TURP).Patients were randomized 2:1 (Aquablation:TURP) in the Waterjet Ablation Therapy for Endoscopic Resection of prostate tissue study. Urodynamics were measured at baseline and 6 months.Urodynamics studies were performed in 66 of the participating subjects at baseline and 6 month follow-up. At mean baseline pDet@qmax was 71 and 73cm H20 in the Aquablation and TURP groups, respectively (P = .7031). At 6-month follow-up, pDet@qmax decreased by 35 and 34cm H20, respectively (P.0001 compared to baseline for both arms) with no significant difference in decrease across groups (P = .8919). A large negative shift in Bladder Outlet Obstruction Index was observed, consistent with a large reduction in the proportion of subjects with obstruction at follow-up compared to baseline (79% to 22% in Aquablation and 96% to 22% in TURP).In this trial, improvements after Aquablation in objective measures of bladder outlet obstruction were similar to those observed after TURP. ClinicalTrials.gov number, NCT02505919. |
| Databáze: | OpenAIRE |
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