Draft genome sequence of tetracycline-resistant Klebsiella oxytoca CCTCC M207023 producing 2,3-butanediol isolated from China
| Autor: | Wei-Jian Wang, Kai-Feng Wang, Xiao-Jun Ji |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) China Virulence Factors Tetracycline 030106 microbiology Immunology Microbiology Genome DNA sequencing Open Reading Frames 03 medical and health sciences 0302 clinical medicine Bacterial Proteins Drug Resistance Multiple Bacterial medicine Immunology and Allergy 030212 general & internal medicine ORFS Butylene Glycols Gene Genetics Whole genome sequencing Base Composition Whole-genome sequencing Whole Genome Sequencing biology Klebsiella oxytoca High-Throughput Nucleotide Sequencing Genome analysis biology.organism_classification QR1-502 Genome Bacterial GC-content medicine.drug |
| Zdroj: | Journal of Global Antimicrobial Resistance, Vol 20, Iss, Pp 160-162 (2020) |
| ISSN: | 2213-7165 |
| Popis: | Objectives Recently, the Gram-negative bacterium Klebsiella oxytoca has been identified as an emerging pathogen. Here we report the draft genome of a 2,3-butanediol-producing strain, K. oxytoca CCTCC M207023, isolated from soil in Nanjing, China. The tetracycline-resistant phenotype and the high yield of 2,3-butanediol was demonstrated. Methods The draft genome of K. oxytoca CCTCC M207023 was determined using an Illumina NovaSeq™ 6000 next-generation DNA sequencing platform. Clean sequencing data were subsequently assembled using SOAPdenovo. Results The draft genome of K. oxytoca CCTCC M207023, comprising 5 658 144 bp and with a GC content of 56.50%, was assembled into 5262 open-reading frames (ORFs). Antimicrobial resistance genes were also annotated. Conclusions The draft genome sequence of K. oxytoca CCTCC M207023 reported here will be a reference for comparative analysis with the antimicrobial resistance mechanisms for the safety of 2,3-butanediol industrial production. |
| Databáze: | OpenAIRE |
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