Outcomes of transcatheter aortic valve replacement for bicuspid aortic stenosis - a systematic review of existing literature
| Autor: | Rajesh Sonani, Apurva Badheka, Samir V. Patel, Palak Patel, Vikas Singh |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Transcatheter aortic medicine.medical_treatment Heart Valve Diseases 030204 cardiovascular system & hematology law.invention Transcatheter Aortic Valve Replacement 03 medical and health sciences 0302 clinical medicine Bicuspid aortic valve Valve replacement Randomized controlled trial Bicuspid Aortic Valve Disease law Internal medicine medicine Humans Pharmacology (medical) In patient 030212 general & internal medicine Randomized Controlled Trials as Topic Early generation business.industry Health Policy General Medicine Aortic Valve Stenosis Equipment Design medicine.disease Surgery Stenosis Treatment Outcome Aortic Valve Cardiology Observational study business |
| Zdroj: | Expert review of pharmacoeconomicsoutcomes research. 17(6) |
| ISSN: | 1744-8379 |
| Popis: | Patients with bicuspid aortic valve (BAV) have traditionally been excluded from large randomized clinical trials involving transcatheter aortic valve replacements (TAVR). Technical enhancements, availability of new generation devices and improved outcomes have led to a marked increase in TAVR volume across the world including off label use in patients with BAV stenosis. Areas covered: In this manuscript, we have reviewed the currently available data regarding safety, efficacy, and outcomes of TAVR in patients with BAV stenosis. 11 large observational studies with near 1300 patients with BAV stenosis were included to summarizes outcomes of TAVR. Expert Commentary: The present review suggested that TAVR may be a safe and feasible treatment modality in BAV stenosis patients. New generation devices were associated with high device success rate whereas higher adverse procedural events were observed in early generation devices. There are no differences in post procedural outcomes with new generation TAVR devices for BAV when compared to tricuspid aortic anatomy. Larger studies are needed to evaluate the long-term outcome and durability of TAVR in patients with BAV. |
| Databáze: | OpenAIRE |
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