Two Cases of Thyrotoxicosis and Euglycemic Diabetic Ketoacidosis Under Sodium-glucose Transport Protein 2 Inhibitor Treatment

Autor:	Takuhei, Hitsuwari, Yuya, Tsurutani, Takahiro, Yamane, Takashi, Sunouchi, Hirofumi, Horikoshi, Rei, Hirose, Yoshitomo, Hoshino, Satoshi, Watanabe, Sho, Katsuragawa, Jun, Saitou
Rok vydání:	2022
Předmět:	Thyrotoxicosis Diabetes Mellitus Type 2 Internal Medicine Humans General Medicine Sodium-Glucose Transport Proteins Sodium-Glucose Transporter 2 Inhibitors Graves Disease Diabetic Ketoacidosis
Zdroj:	Internal Medicine. 61:3069-3075
ISSN:	1349-7235 0918-2918
Popis:	Thyrotoxicosis and sodium-glucose transport protein 2 inhibitors (SGLT2is) are associated with the induction of euglycemic diabetic ketoacidosis (euDKA). We herein report two cases of euDKA in patients with diabetes mellitus wherein both thyrotoxicosis and SGLT2i treatment were the underlying causes. One patient developed thyrotoxicosis during the course of type 2 diabetes mellitus, whereas the other patient was suspected of developing slowly progressive insulin-dependent diabetes mellitus during the course of Graves' disease. Although such cases are rare, there is some concern that similar cases may occur because of the increased frequency of SGLT2i use in recent years.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efb18412b516b065b9d0933c6d3798f https://doi.org/10.2169/internalmedicine.8830-21 Zobrazit plný text záznamu