Quantitative evaluation of WEB shape modification: A five-year follow-up study

Autor: Fakhreddine Boustia, Kevin Janot, Denis Herbreteau, Ana Paula Narata, R. Bibi, Laurent Pierot, Chrysanthi Papagiannaki, Basile Kerleroux, Guillaume Charbonnier, Aymeric Amelot, Aymeric Rouchaud
Přispěvatelé: UMR930, Imagerie et cerveau, Université Francois Rabelais [Tours], CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Hôpital Lariboisière, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), University Hospital of Besançon, Neuroradiology Department, 3, boulevard Alexandre-Fleming, 25000 Besançon, France, Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), CHU Rouen, Normandie Université (NU), Service de Radiologie et Imagerie Médicale [CHU Limoges], CHU Limoges, Hôpital Maison Blanche, Centre Hospitalier Universitaire de Reims (CHU Reims), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Lariboisière-Université Paris Diderot - Paris 7 (UPD7)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: American Journal of Neuroradiology
American Journal of Neuroradiology, American Society of Neuroradiology, 2019, ⟨10.1016/j.neurad.2019.02.010⟩
ISSN: 0195-6108
Popis: Background and purpose Web shape modification (WSM) has previously been associated with aneurysm recurrence. We report here our five-year experience of WEB device use with a quantitative approach of the WSM phenomenon. Methods From July 2012 to July 2017, 50 patients with 51 unruptured aneurysms treated with the WEB device have been prospectively enrolled in our data base and retrospectively analyzed. An independent “core lab” evaluated anatomical results and potential WSM in DSA follow-up. We defined the WSM ratio (WSMr) as a relative index between the height and the width of the device in working projections which gave an evaluation of the device deformation over the time. Results During the total follow-up period, WSM was observed in 35/48 aneurysms (72.9%). Adequate occlusion rates were 87.0% and 92.6% with and without WSM respectively (P = 0.65). 30 out the 35 (85.7%) shape modifications were already noticed at short-term follow-up (6-month DSA). 33 patients had 2 DSA controls and WSMr measurements were available in 24 patients: 18 (75%) with WSM and 6 (25%) without WSM. In the group with WSM, WSMr values were 0.80 in post-embolization, 0.52 at the first DSA angiogram and 0.42 at the second DSA angiogram. Conclusion WEB shape modification was observed in more than half of cases but with no influence regarding adequate occlusion rate. This quantitative approach of WSM highlights that this phenomenon appears to be early and progressive over time. This supports the hypothesis that WSM could be more probably related to aneurysm healing rather than external compression.
Databáze: OpenAIRE