Migraine Headache Treated with Famciclovir and Celecoxib: A Case Report
| Autor: | Maki Morimoto, Bradford Lee Napier, Erin NaPier |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Severe headache Migraine Disorders Antiviral Agents 03 medical and health sciences Young Adult 0302 clinical medicine medicine Humans Young adult 2-Aminopurine Hsv infection Cyclooxygenase 2 Inhibitors business.industry Famciclovir Herpes Simplex General Medicine medicine.disease Dermatology Pathophysiology 030104 developmental biology Treatment Outcome Migraine Celecoxib Female Headaches medicine.symptom Clinical Medicine business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | The Permanente journal. 22 |
| ISSN: | 1552-5775 |
| Popis: | Introduction Herpes simplex virus (HSV) has been speculated to play a role in migraine headache pathophysiology. We present the first successful migraine headache treatment with therapy specifically targeting HSV infection. Case presentation A previously healthy 21-year-old white woman presented with a severe headache and was diagnosed with severe migraine headache disorder. She initially was treated with standard migraine headache medications without symptomatic improvement. She was then given famciclovir and celecoxib. The patient fully recovered within days and continues to enjoy significant reduction in severity and frequency of symptoms. Discussion Famciclovir and celecoxib may work synergistically against HSV. The virus may play a role in the pathophysiology of migraine headaches, and this is the first case report of successful migraine headache treatment with these medications. Further studies are needed to elucidate the efficacy of these medications in treating migraine disorder. |
| Databáze: | OpenAIRE |
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