A Suboptimal Diet is Associated with Poorer Cognition: The NUDAD Project
| Autor: | Philip Scheltens, Marian A. E. de van der Schueren, Wiesje M. van der Flier, Barbara J. H. Verhaar, Marjolein Visser, Francisca A. de Leeuw, Astrid S. Doorduijn, Linda M.P. Wesselman, Jay L.P. Fieldhouse, Ted Koene, Ondine van de Rest, Maartje I. Kester |
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| Přispěvatelé: | Amsterdam Neuroscience - Neurodegeneration, Neurology, Internal medicine, AGEM - Endocrinology, metabolism and nutrition, APH - Aging & Later Life, APH - Health Behaviors & Chronic Diseases, APH - Personalized Medicine, APH - Methodology, ACS - Atherosclerosis & ischemic syndromes, Vascular Medicine, ACS - Diabetes & metabolism, ACS - Amsterdam Cardiovascular Sciences, Nutrition and Health, APH - Societal Participation & Health |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Gerontology food intake Saturated fat Disease Recommended Dietary Allowances Eating Executive Function Cognition 0302 clinical medicine Risk Factors Food intake Vegetables 030212 general & internal medicine Neuropsychological functioning Cognitive decline Nutrition and Dietetics Trans Fatty Acids Nutritional Biology nutrition Elder Nutritional Physiological Phenomena SDG 1 - No Poverty Female Alcohol intake Diet Healthy lcsh:Nutrition. Foods and food supply neuropsychological functioning Alcohol Drinking Context (language use) lcsh:TX341-641 Article 03 medical and health sciences mild cognitive impairment Alzheimer Disease medicine Humans Dementia Cognitive Dysfunction Effects of sleep deprivation on cognitive performance Nutrition VLAG business.industry Malnutrition Mild cognitive impairment Feeding Behavior medicine.disease Dietary Fats Patient Compliance business 030217 neurology & neurosurgery Food Science dementia |
| Zdroj: | Nutrients, Vol 12, Iss 3, p 703 (2020) Nutrients, 12(3):703. Multidisciplinary Digital Publishing Institute (MDPI) Nutrients 12 (2020) 3 Nutrients, 12 Fieldhouse, J L P, Doorduijn, A S, de Leeuw, F A, Verhaar, B J H, Koene, T, Wesselman, L M P, Schueren, M D V D, Visser, M, Rest, O V D, Scheltens, P, Kester, M I & Flier, W M V D 2020, ' A Suboptimal Diet is Associated with Poorer Cognition : The NUDAD Project ', Nutrients, vol. 12, no. 3, 703 . https://doi.org/10.3390/nu12030703 Nutrients Volume 12 Issue 3 Nutrients, 12(3) Fieldhouse, J L P, Doorduijn, A S, de Leeuw, F A, Verhaar, B J H, Koene, T, Wesselman, L M P, de van der Schueren, M, Visser, M, van de Rest, O, Scheltens, P, Kester, M I & van der Flier, W M 2020, ' A suboptimal diet is associated with poorer cognition : The NUDAD project ', Nutrients, vol. 12, no. 3, 703, pp. 1-10 . https://doi.org/10.3390/nu12030703 Nutrients, 12(3):703, 1-10. Multidisciplinary Digital Publishing Institute (MDPI) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu12030703 |
| Popis: | Nutrition is one of the modifiable risk factors for cognitive decline and Alzheimer&rsquo s disease (AD) dementia, and is therefore highly relevant in the context of prevention. However, knowledge of dietary quality in clinical populations on the spectrum of AD dementia is lacking, therefore we studied the association between dietary quality and cognitive impairment in Alzheimer&rsquo s disease (AD) dementia, mild cognitive impairment (MCI) and controls. We included 357 participants from the NUDAD project (134 AD dementia, 90 MCI, 133 controls). We assessed adherence to dietary guidelines (components: vegetables, fruit, fibers, fish, saturated fat, trans-fat, salt, and alcohol), and cognitive performance (domains: memory, language, visuospatial functioning, attention, and executive functioning). In the total population, linear regression analyses showed a lower vegetable intake is associated with poorer global cognition, visuospatial functioning, attention and executive functioning. In AD dementia, lower total adherence to dietary guidelines and higher alcohol intake were associated with poorer memory, a lower vegetable intake with poorer global cognition and executive functioning, and a higher trans-fat intake with poorer executive functioning. In conclusion, a suboptimal diet is associated with more severely impaired cognition&mdash this association is mostly attributable to a lower vegetable intake and is most pronounced in AD dementia. |
| Databáze: | OpenAIRE |
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