Risk Factors Associated with Mortality among Patients with COVID-19: Analysis of a Cohort of 1213 Patients in a Tertiary Healthcare Center

Autor: Carlos Alfonso Romero-Gameros, Guadalupe Vargas-Ortega, Mario Enrique Rendón-Macias, Carlos Fredy Cuevas-García, Tania Colín-Martínez, Luis Alejandro Sánchez-Hurtado, Lourdes Josefina Balcázar-Hernández, Iván Emilio De la Cruz-Rodríguez, Enid Karina Pérez-Dionisio, Perla Michelle Retana-Torres, Elsy Sarahí García-Montesinos, Mayra Alejandra López-Moreno, Marielle Intriago-Alor, Salomón Waizel-Haiat, Baldomero González-Virla
Rok vydání: 2022
Předmět:
Zdroj: Journal of Clinical Medicine; Volume 11; Issue 10; Pages: 2780
ISSN: 2077-0383
Popis: The presence of cardio-metabolic and respiratory comorbidities, immunosuppression, and chronic kidney disease have been associated with an increase in mortality from COVID-19. The objective of this study is to establish the risk factors associated with 30-day mortality in a cohort of hospitalized patients with COVID-19. This paper conducts a retrospective and analytical study of patients hospitalized for COVID-19 in a tertiary care center. A Cox proportional hazard analysis was performed to estimate the association of comorbidities with 30-day mortality. A total of 1215 patients with a median age of 59 years were included. In the adjusted Cox proportional hazards regression model, hypothyroidism, D-dimer ≥ 0.8 μg/mL, LHD ≥ 430 IU/L, CRP ≥ 4.83 ng/mL, and triglycerides ≥ 214 mg/dL were associated with an increased risk of death. The presence of a history of hypothyroidism and biomarkers (D-dimer, lactic dehydrogenase, CRP, and triglycerides) were associated with an increase in mortality in the studied cohort.
Databáze: OpenAIRE
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