Taking advantage of pathogen diversity and immune priming to minimize disease prevalence in host mixtures: a model

Autor: Didier Andrivon, Ludovic Mailleret, Florence Val, Frédéric Grognard, Frédéric Hamelin, Pauline Clin
Přispěvatelé: Institut de Génétique, Environnement et Protection des Plantes (IGEPP), Université de Rennes (UR)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Biological control of artificial ecosystems (BIOCORE), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire d'océanographie de Villefranche (LOV), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de la Mer de Villefranche (IMEV), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de la Mer de Villefranche (IMEV), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Côte d'Azur (UCA), Institut Sophia Agrobiotech (ISA), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Côte d'Azur (UCA), Pauline Clin is supported by a Ph.D. fellowship from the INRAE 'Plant Health and the Environment' Division and the Council of Brittany Region. Frédéric Hamelin acknowledges funding from the INRAE 'Plant Health and the Environment' Division., Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Nice Sophia Antipolis (... - 2019) (UNS)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
0106 biological sciences
Genotype
[MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS]
Plant Immunity
Virulence
Plant Science
Priming (agriculture)
Biology
01 natural sciences
polymorphism
induced resistance
03 medical and health sciences
Immune system
[SDV.EE.ECO]Life Sciences [q-bio]/Ecology
environment/Ecosystems
[INFO.INFO-AU]Computer Science [cs]/Automatic Control Engineering
Prevalence
priming
Pathogen
Plant Diseases
030304 developmental biology
2. Zero hunger
Genetics
0303 health sciences
avirulent
Plant disease
[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy
virulence
Cultivar mixtures
Host-Pathogen Interactions
gene-for-gene
systemic acquired resistance
Disease Susceptibility
Agronomy and Crop Science
Systemic acquired resistance
010606 plant biology & botany
Zdroj: Phytopathology
Phytopathology, 2021, 111 (7), pp.1219-1227. ⟨10.1094/PHYTO-09-20-0429-R⟩
Phytopathology, American Phytopathological Society, 2021, 111 (7), pp.1219-1227. ⟨10.1094/PHYTO-09-20-0429-R⟩
ISSN: 0031-949X
DOI: 10.1094/PHYTO-09-20-0429-R⟩
Popis: International audience; Host mixtures are a promising method for agroecological plant disease control. Plant immunity is key to the success of host mixtures against polymorphic pathogen populations. This immunity results from priming-induced cross-protection, whereby plants able to resist infection by specific pathogen genotypes become more resistant to other pathogen genotypes. Strikingly, this phenomenon was absent from mathematical models aiming at designing host mixtures. We developed a model to specifically explore how priming affects the coexistence of two pathogen genotypes in host mixtures composed of two host genotypes and how it affects disease prevalence. The main effect of priming is to reduce the coexistence region in the parameter space (due to the cross-protection) and to generate a singular mixture of resistant and susceptible hosts corresponding to the maximal reduction disease prevalence (in absence of priming, a resistant pure stand is optimal). The epidemiological advantage of host mixtures over a resistant pure stand thus appears as a direct consequence of immune priming. We also showed that there is indirect cross-protection between host genotypes in a mixture. Moreover, the optimal mix prevents the emergence of a resistance-breaking pathogen genotype. Our results highlight the importance of considering immune priming to design optimal and sustainable host mixtures.
Databáze: OpenAIRE
Externí odkaz: