Neuroblastoma with ovarian and pancreatic metastasis
| Autor: | Takashi Tsutsuno, Toshihiro Fujiki, Kentaro Hayashi, Kazuhiro Noguchi, Yasuhiro Ikawa, Honami Mizushima, Kozo Nomura, Rie Kuroda, Seisho Sakai, Raita Araki, Takatoshi Abe |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Chemotherapy
Pathology medicine.medical_specialty RD1-811 business.industry Pancreatic metastasis medicine.medical_treatment Ovary Ovarian metastasis medicine.disease Pediatrics RJ1-570 Metastasis Radiation therapy Ovarian tumor Neuroblastoma medicine.anatomical_structure Pediatrics Perinatology and Child Health medicine Surgery Pancreas business Lymph node |
| Zdroj: | Journal of Pediatric Surgery Case Reports, Vol 73, Iss, Pp 101996-(2021) |
| ISSN: | 2213-5766 |
| Popis: | Neuroblastoma metastasis to the pancreas and ovaries is rare. We report a 12-year-old girl diagnosed with primary left adrenal neuroblastoma and metastases to the local lymph nodes, left orbit, left ovary, and multiple bones. After 4 courses of chemotherapy, the orbital and bone metastases disappeared; the ovarian tumor remained and the lymph node metastases were shown to be pancreatic metastases. Left adrenal tumor resection with spleen-preserving partial pancreas resection and left ovariectomy was performed. Pathological examination of surgical specimens showed viable tumor cells in the ovary but none in the pancreas. Additional chemotherapy, autologous bone marrow transplantation, I131-MIBG radiotherapy, and radiation therapy were performed after surgery. This case was a case where it was possible to resect a rare metastatic site, and it is thought that there are many points to discuss about the metastatic pathway, evaluation about reactivity of chemotherapy, and indication about excision of metastatic lesions. |
| Databáze: | OpenAIRE |
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