Analysis of risk factors for ventilator-associated pneumonia in a multidisciplinary intensive care unit
| Autor: | H. Anastasiou, M. Yannacou, E. Sofianos, D. C. Sofianou, T. C. Constandinidis |
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| Rok vydání: | 2000 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Time Factors Fever medicine.medical_treatment Infections law.invention Catheters Indwelling law Risk Factors Internal medicine Intensive care medicine Pneumonia Bacterial Humans Prospective Studies Risk factor Mechanical ventilation Ventilators Mechanical business.industry Mortality rate Incidence Ventilator-associated pneumonia General Medicine Odds ratio Length of Stay medicine.disease Intensive care unit Respiration Artificial Survival Analysis respiratory tract diseases Surgery Pneumonia Intensive Care Units Infectious Diseases Regression Analysis business |
| Zdroj: | European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology. 19(6) |
| ISSN: | 0934-9723 |
| Popis: | A prospective study was conducted to determine the incidence, risk factors and pathogens of ventilator-associated pneumonia (VAP) in 198 patients requiring mechanical ventilation for more than 48 hours. VAP occurred in 67 (33.8%) patients. Risk factors associated with VAP were admission APACHE II score20 (odds ratio [OR] 4.77, 95% confidence interval [CI] 2.04-11.27, P0.001), mechanical ventilation10 days (OR 44.4, 95% CI 2.16-26.7, P0.0001), ICU length of stay10 days (OR 9.4, 95% CI 3.55-25.65, P0.0001), and admission PaO2/FiO2 ratio200mmHg (OR 3.4, 95% CI 1.00-11.41, P0.05). Logistic regression analysis showed a relationship between VAP and length of stay in ICU, duration of fever and presence of catheter-related infection. The pathogens isolated were predominantly gram-negative bacteria (83.2%), with a high proportion of Acinetobacter spp. (35%) resistant to commonly used antimicrobial agents. The mortality rate was not influenced by VAP. |
| Databáze: | OpenAIRE |
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