Current concepts of active vasodilation in human skin
| Autor: | Casey Hollowed, Brett J. Wong |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Hyperthermia
medicine.medical_specialty Sympathetic nervous system microdialysis Physiology Vasoactive intestinal peptide Comprehensive Review Human skin Context (language use) Vasodilation 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine nitric oxide Physiology (medical) Internal medicine medicine neurokinin-1 receptors sympathetic nervous system thermoregulation integumentary system Chemistry 030229 sport sciences Thermoregulation hyperthermia medicine.disease Sudomotor Endocrinology medicine.anatomical_structure vasoactive intestinal polypeptide neuropeptides EDHF Neuroscience |
| Zdroj: | Temperature: Multidisciplinary Biomedical Journal |
| ISSN: | 2332-8959 2332-8940 |
| DOI: | 10.1080/23328940.2016.1200203 |
| Popis: | In humans, an increase in internal core temperature elicits large increases in skin blood flow and sweating. The increase in skin blood flow serves to transfer heat via convection from the body core to the skin surface while sweating results in evaporative cooling of the skin. Cutaneous vasodilation and sudomotor activity are controlled by a sympathetic cholinergic active vasodilator system that is hypothesized to operate through a co-transmission mechanism. To date, mechanisms of cutaneous active vasodilation remain equivocal despite many years of research by several productive laboratory groups. The purpose of this review is to highlight recent advancements in the field of cutaneous active vasodilation framed in the context of some of the historical findings that laid the groundwork for our current understanding of cutaneous active vasodilation. |
| Databáze: | OpenAIRE |
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