Chronic salmonella septicemia and malabsorption of vitamin A
| Autor: | Zoheir Farid, M M Mikhail, S Bassily, M M Mansour |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
Male Vitamin medicine.medical_specialty Malabsorption Adolescent Anemia medicine.medical_treatment Salmonella septicemia Population Medicine (miscellaneous) Gastroenterology chemistry.chemical_compound Malabsorption Syndromes Sepsis Internal medicine medicine Humans Schistosomiasis Vitamin A education education.field_of_study Nutrition and Dietetics business.industry Carotene Anemia Aplastic Salmonella typhi medicine.disease Vitamin A deficiency Intestinal Absorption chemistry Salmonella paratyphi A Bacteremia Salmonella Infections Immunology Egypt business |
| Zdroj: | The American Journal of Clinical Nutrition. 32:319-324 |
| ISSN: | 0002-9165 |
| DOI: | 10.1093/ajcn/32.2.319 |
| Popis: | Vitamin A absorption was studied in two groups of subjects using a vitamin A tolerance test. The first group consisted of 15 patients with chronic salmonella bacteremia associated with Schisiosoma mansoni infection and refractory anemia. The second group consisted of 11 patients with active S. mansoni infection associated with anemia but without concurrent salmonel- losis. None of the patients had clinical signs of vitamin A deficiency. Ten healthy Egyptians of the same age group with no evidence of any infection served as controls for this absorption test. On admission the mean values of fasting vitamin A and carotene levels in the first group were lower than those in the second group and both levels were significantly lower (P < 0.00 1) than the control group mean level. Similarly, the mean peak vitamin A rise after the test dose in the first group was significantly lower (P < 0.01) than the mean peak rise in the second group and both were significantlylower (P < 0.00 1) than the control group mean level. After receiving the appropriate therapy, however, the mean fasting vitamin A and carotene levels showed significant increase in both groups (P < 0.001). There was also a significant improvement (P < 0.001) in vitamin A absorption of the first group and insignificant increase in the second group but both groups remained significantly lower (P < 0.00 1) than the control group mean absorption level. The results of this study suggest that chronic salmonellosis may cause gross impairment in vitamin A absorption and may contribute significantly to the wide prevalence of vitamin A deficiency in a given population with borderline dietary intake. Am. J. Clin. Nuir. 32: 3 19-324, 1979. |
| Databáze: | OpenAIRE |
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