Intracellular concentration of potassium and other elements in vaginal epithelial cells stimulated by estradiol administration
| Autor: | Thomas B. Pool, Nancy K. R. Smith, Ivan L. Cameron |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Cytoplasm
medicine.medical_specialty Time Factors Physiology Potassium Clinical Biochemistry chemistry.chemical_element Basal (phylogenetics) Chlorides Dry weight Internal medicine medicine Animals Magnesium Castration Vaginal epithelium Estradiol Chemistry Sodium Phosphorus Cell Biology Rats Endocrinology Vagina Ovariectomized rat Female Growth stimulation Cell Division Sulfur Intracellular Electron Probe Microanalysis |
| Zdroj: | Journal of Cellular Physiology. 104:121-125 |
| ISSN: | 1097-4652 0021-9541 |
| DOI: | 10.1002/jcp.1041040115 |
| Popis: | Electron probe x-ray microanalysis was used to measure cytoplasmic elemental content (in mmoles/kg dry weight) of the basal layer of cells of the vaginal epithelium of ovariectomized rats. Measurements were made both before estradiol injection and at 2 hr, 17 hr, and 24 hr after estradiol administration. Mitotic figures first appeared in the basal cell layer at 24 hr. During the course of the study significant time-dependent differences were seen in the content of all elements measured. A pattern of change in cytoplasmic content was seen for Na, P, S, and Cl; all of which decrease significantly by 17 hr and then return to approximately the nonstimulated concentration by 24 hr. On the other hand K, and to a lesser extent Mg, show an early and continued increase in cytoplasmic content after estradiol injection. Thus, the marked increase in the intracytoplasmic content of K in the estradiol treated cells suggests that K, or the ratio of Na to K, may be directly or indirectly involved in growth stimulation. |
| Databáze: | OpenAIRE |
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