Microalgae biomass intake positively modulates serum lipid profile and antioxidant status
| Autor: | Eduardo Jacob-Lopes, Mário Roberto Maróstica, Cinthia Baú Betim Cazarin, Renato Grimaldi, Tatiele Casagrande do Nascimento, Leila Queiroz Zepka, Adriana Zerlotti Mercadante, Eder Muller Risso, Jaime Amaya-Farfan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Antioxidant medicine.medical_treatment Glutathione reductase Lipid peroxidation Medicine (miscellaneous) Spleen 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology medicine TX341-641 Food science Fatty acids chemistry.chemical_classification Green microalgae Kidney 030109 nutrition & dietetics Nutrition and Dietetics medicine.diagnostic_test Nutrition. Foods and food supply Glutathione peroxidase 04 agricultural and veterinary sciences 040401 food science Carotenoids Antioxidant potential medicine.anatomical_structure chemistry Amino acids Lipid profile Food Science Lipoprotein |
| Zdroj: | Journal of Functional Foods, Vol 58, Iss, Pp 11-20 (2019) |
| ISSN: | 1756-4646 |
| Popis: | This study investigated the biocompounds present in the Scenedesmus obliquus biomass and evaluated the effect of the supplementation in the serum lipid profile and tissues antioxidant status of mice. Male mice were divided into control and microalgae biomass treated groups (T1 = 400 and T2 = 800 mg·kg−1 bw·d−1) for four weeks. Serum and tissues (heart, liver, kidneys, and spleen) were analyzed. The microalgae biomass presented a valuable content of biocompounds. In serum, the T2 treatment promoted an increase in high-density lipoprotein but also triglycerides levels. The T1 increased glutathione peroxidase (kidney) and antioxidant potential of all tissues, while T2 treatment was able to raise the glutathione reductase (liver) and glutathione peroxidase (kidneys) activities, as well as the heart antioxidant potential. The two doses reduced lipid peroxidation in all tissues. Thus, we observed that S. obliquus biomass (T1) exerted a protective influence against tissue lipid peroxidation. |
| Databáze: | OpenAIRE |
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