Paauglių, sergančių idiopatine generalizuota epilepsija, pažinimo funkcijos

Autor: Virginija Adomaitienė, Vitalija Marmienė, Milda Endzinienė, Giedrė Jurkevičienė, Giedrė Gelžinienė
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Medicina; Volume 47; Issue 6; Pages: 44
Medicina, Kaunas : Lietuvos sveikatos mokslų universitetas, 2011, t. 47, Nr. 6, p. 313-319
ISSN: 1648-9144
1010-660X
DOI: 10.3390/medicina47060044
Popis: Disorders of executive functioning have recently been reported in patients with juvenile myoclonic epilepsy (JME); however, data on other syndromes of generalized idiopathic epilepsy (IGE) other than JME, especially in adolescence, are scarce. The aim of this study was to explore specific executive functions in a group of adolescents with IGE of short duration and to evaluate the possible factors that might influence these functions. Material and Methods. Neuropsychological investigation of executive functions (the Verbal Fluency Test, the Five-Point Test, the Trail-Making Test, and the Stroop test) was performed in 59 patients aged 14–17 years and meeting the diagnostic criteria for IGE, and in the group of 59 agematched controls without any history of epilepsy. Results. The IGE group subjects scored worse than the controls in most of the executive function tests: phonemic (P=0.008) and semantic (P=0.001) word fluency, figural fluency (P=0.008), visual search and sequencing of numbers (P=0.001), and alternate number-letter sequencing (P=0.018). None of the test scores differed between the new-onset and the established IGE groups, or between the groups of cases with and without myoclonias. No relationship between executive functioning and gender, age, duration or activity of epilepsy, treatment, or epileptiform discharges on electroencephalography was found. Conclusions. Executive dysfunction was present in adolescents with JME and other syndromes of IGE, manifesting with generalized tonic-clonic seizures without myoclonias, despite short duration and benign course of epilepsy
Databáze: OpenAIRE