Paauglių, sergančių idiopatine generalizuota epilepsija, pažinimo funkcijos
| Autor: | Virginija Adomaitienė, Vitalija Marmienė, Milda Endzinienė, Giedrė Jurkevičienė, Giedrė Gelžinienė |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Adolescent idiopathic generalized epilepsy executive functions myoclonias generalized tonicclonic seizures Audiology Neuropsychological Tests Idiopathic generalized epilepsy Epilepsy Executive Function Epilepsy generalized In adolescence Executive function Myoclonus Medicine Verbal fluency test Humans 616.853-053.6 [udc] business.industry General Medicine medicine.disease Executive functions Cross-Sectional Studies Epilepsy Generalized Female Juvenile myoclonic epilepsy medicine.symptom business Executive dysfunction Stroop effect |
| Zdroj: | Medicina; Volume 47; Issue 6; Pages: 44 Medicina, Kaunas : Lietuvos sveikatos mokslų universitetas, 2011, t. 47, Nr. 6, p. 313-319 |
| ISSN: | 1648-9144 1010-660X |
| DOI: | 10.3390/medicina47060044 |
| Popis: | Disorders of executive functioning have recently been reported in patients with juvenile myoclonic epilepsy (JME); however, data on other syndromes of generalized idiopathic epilepsy (IGE) other than JME, especially in adolescence, are scarce. The aim of this study was to explore specific executive functions in a group of adolescents with IGE of short duration and to evaluate the possible factors that might influence these functions. Material and Methods. Neuropsychological investigation of executive functions (the Verbal Fluency Test, the Five-Point Test, the Trail-Making Test, and the Stroop test) was performed in 59 patients aged 14–17 years and meeting the diagnostic criteria for IGE, and in the group of 59 agematched controls without any history of epilepsy. Results. The IGE group subjects scored worse than the controls in most of the executive function tests: phonemic (P=0.008) and semantic (P=0.001) word fluency, figural fluency (P=0.008), visual search and sequencing of numbers (P=0.001), and alternate number-letter sequencing (P=0.018). None of the test scores differed between the new-onset and the established IGE groups, or between the groups of cases with and without myoclonias. No relationship between executive functioning and gender, age, duration or activity of epilepsy, treatment, or epileptiform discharges on electroencephalography was found. Conclusions. Executive dysfunction was present in adolescents with JME and other syndromes of IGE, manifesting with generalized tonic-clonic seizures without myoclonias, despite short duration and benign course of epilepsy |
| Databáze: | OpenAIRE |
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