Acylphloroglucinol and xanthones from Hypericum ellipticum
| Autor: | Antonio González-Sarrías, Kylie B. Manning, Geneive E. Henry, Navindra P. Seeram, Elyse M. Petrunak, Michelle Lebo |
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| Rok vydání: | 2011 |
| Předmět: |
biology
Traditional medicine Xanthones Hypericum perforatum Clusiaceae Plant Science General Medicine Phloroglucinol Horticulture Pharmacognosy biology.organism_classification Biochemistry Human colon cancer Inhibitory Concentration 50 chemistry.chemical_compound Hypericum ellipticum chemistry Cell Line Tumor Botany Xanthone Humans Molecular Biology Hypericum Human colon |
| Zdroj: | Phytochemistry. 72:662-667 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/j.phytochem.2011.01.032 |
| Popis: | An acylphloroglucinol, elliptophenone A, and two xanthones, elliptoxanthone A and elliptoxanthone B, were isolated from the aerial portions of Hypericum ellipticum together with three known xanthones, 1,3,7-trihydroxy-8-(3-methyl-2-butenyl)-9H-xanthen-9-one, 1,6-dihydroxy-4-methoxy-9H-xanthen-9-one, and 1,4,5-trihydroxy-9H-xanthen-9-one. Their structures were determined by spectroscopic analyses. The acylphloroglucinol and xanthones were evaluated for cytotoxicity using three human colon cancer cell lines cell lines (HT-29, HCT-116 and Caco-2) and a normal human colon cell line (CCD-18Co). |
| Databáze: | OpenAIRE |
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