Lens Status as the Single Most Important Factor in Endothelium Protection After Vitreous Surgery
| Autor: | Amit Jain, Rajvardhan Azad, Brijesh Takkar, Babanrao Anil Gangwe, Shorya Vardhan Azad, Deepankur Mahajan |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Pars plana medicine.medical_specialty Corneal endothelium Adolescent Pseudophakia Endothelium medicine.medical_treatment Cell Count Vitrectomy Aphakia Postcataract Ophthalmology Lens Crystalline medicine Humans Decompensation Prospective Studies Child Prospective cohort study Aged Aged 80 and over Viscosupplements business.industry Endothelium Corneal Corneal Endothelial Cell Loss Middle Aged Surgery Endothelial stem cell medicine.anatomical_structure Female Complication business |
| Zdroj: | Cornea. 33:1061-1065 |
| ISSN: | 0277-3740 |
| DOI: | 10.1097/ico.0000000000000218 |
| Popis: | PURPOSE The aim of this study was to evaluate the effect of vitreous surgery on the corneal endothelium. METHODS A total of 113 eyes undergoing pars plana vitrectomy for variable indications at a tertiary care center were included prospectively. The mean age was 41 years (range, 9-84 years), and 60% were male. The endothelial cell count was measured preoperatively and on postoperative day 1, 30, 90, and 180. The rate of endothelial cell loss was measured and analysis performed based on gauge of surgery, lens status, and vitreous substitute used. RESULTS About 7.6% of endothelial cells were lost at postoperative day 1. This rate had decreased to 2.5% in the first 30 days, 1.5% between days 30 and 90, and 1.4% between days 90 and 180. Significant difference in endothelial cell loss was noted on day 1 between phakic (7.2%), pseudophakic (6.4%), and aphakic (11.4%) eyes with similar results at 6 months. There was no significant difference between the gauges of surgery (20 G vs. 23 G) or the vitreous substitutes used (air vs. gas vs. silicone oil) on day 1 or at 6 months. CONCLUSIONS Endothelial decompensation is an important complication of vitreoretinal surgery. Precautions should be taken in aphakics and patients requiring anterior segment manipulation. Although there is immediate cell loss, the rate of cell loss approaches normative values with time. |
| Databáze: | OpenAIRE |
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