Iron overload in the liver diagnostic and quantification
| Autor: | Jose M. Alústiza, Maite Uranga, Agustin Castiella, Jose I. Emparanza, Jose Artetxe, Maria D. de Juan |
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| Rok vydání: | 2006 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.diagnostic_test business.industry Iron General Medicine medicine.disease Bioinformatics Magnetic Resonance Imaging Liver Hereditary hemochromatosis Biopsy medicine Hepatic biopsy Humans Radiology Nuclear Medicine and imaging Hepatic iron Hemochromatosis business |
| Zdroj: | European journal of radiology. 61(3) |
| ISSN: | 0720-048X |
| Popis: | Hereditary Hemochromatosis is the most frequent modality of iron overload. Since 1996 genetic tests have facilitated significantly the non-invasive diagnosis of the disease. There are however many cases of negative genetic tests that require confirmation by hepatic iron quantification which is traditionally performed by hepatic biopsy. There are many studies that have demonstrated the possibility of performing hepatic iron quantification with Magnetic Resonance. However, a consensus has not been reached yet regarding the technique or the possibility to reproduce the same method of calculus in different machines. This article reviews the state of the art of the question and delineates possible future lines to standardise this non-invasive method of hepatic iron quantification. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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