Mānuka Oil—A Review of Antimicrobial and Other Medicinal Properties
| Autor: | Andrew Bartholomaeus, Gregory M. Peterson, Cynthia Mathew, Wubshet Tesfaye, Phil Rasmussen, Jackson Thomas, Manab Sharma |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
antiparasitic therapeutic properties Pharmaceutical Science lcsh:Medicine lcsh:RS1-441 Review 01 natural sciences law.invention lcsh:Pharmacy and materia medica 03 medical and health sciences law Drug Discovery Essential oil 030304 developmental biology mānuka oil medicinal 0303 health sciences Leptospermum scoparium biology business.industry lcsh:R Antimicrobial biology.organism_classification Biotechnology 010602 entomology antibacterial Clinical evidence Molecular Medicine antimicrobial business PubChem |
| Zdroj: | Pharmaceuticals, Vol 13, Iss 343, p 343 (2020) Pharmaceuticals |
| ISSN: | 1424-8247 |
| Popis: | Mānuka oil is an essential oil derived from Leptospermum scoparium, a plant that has been used by the indigenous populations of New Zealand and Australia for centuries. Both the extracted oil and its individual components have been associated with various medicinal properties. Given the rise in resistance to conventional antibiotics, natural products have been targeted for the development of antimicrobials with novel mechanism of action. This review aimed to collate available evidence on the antimicrobial, anti-parasitic and anti-inflammatory activities of mānuka oil and its components. A comprehensive literature search of was conducted using PubMed and Embase (via Scopus) targeting articles from database inception until June 2020. Chemical structures and IUPAC names were sourced from PubChem. Unpublished information from grey literature databases, Google search, targeted websites and Google Patents were also included. The present review found extensive in vitro data supporting the antimicrobial effects of mānuka oil warrants further clinical studies to establish its therapeutic potential. Clinical evidence on its efficacy, safety and dosing guidelines are necessary for its implementation for medical purposes. Further work on regulation, standardization and characterization of the medicinal properties of mānuka oil is required for establishing consistent efficacy of the product. |
| Databáze: | OpenAIRE |
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