Impaired renal function is a major determinant of left ventricular diastolic dysfunction: assessment by stress myocardial perfusion imaging

Autor: Kenji Iino, Takashi Koyama, Hiroshi Ito, Hiroyuki Watanabe, Masaru Ishida, Wakana Sato, Toshimitsu Kosaka
Rok vydání: 2013
Předmět:
Male
medicine.medical_specialty
Left ventricular diastolic function
Gated SPECT
Myocardial Ischemia
Renal function
Coronary Artery Disease
Single-photon emission computed tomography
urologic and male genital diseases
Kidney
Coronary artery disease
Myocardial perfusion imaging
Electrocardiography
Ventricular Dysfunction
Left
Stress
Physiological
Internal medicine
Chronic kidney disease
medicine
Humans
Radiology
Nuclear Medicine and imaging
cardiovascular diseases
Estimated glomerular filtration rate
Aged
Tomography
Emission-Computed
Single-Photon
medicine.diagnostic_test
business.industry
Myocardial Perfusion Imaging
General Medicine
Middle Aged
medicine.disease
medicine.anatomical_structure
Radiology Nuclear Medicine and imaging
Cardiology
Left ventricular diastolic dysfunction
Female
Original Article
business
Glomerular Filtration Rate
Zdroj: Annals of Nuclear Medicine
ISSN: 1864-6433
Popis: Objective Relationships between myocardial scintigraphic parameters and renal function have not been fully determined. We investigated correlations between estimated glomerular filtration rate (eGFR) and left ventricular (LV) diastolic function using stress electrocardiographic (ECG)-gated myocardial single photon emission computed tomography (SPECT). Methods We enrolled 136 consecutive patients with suspected coronary artery disease (CAD) who were assessed using technetium-99m stress ECG-gated myocardial SPECT. We evaluated SPECT images using 17-segment defect scores graded on a 5-point scale, summed stress score, summed rest score and summed difference score (SDS). The parameters for assessing LV diastolic function were peak filling rate (PFR), 1/3 mean filling rate and time to peak filling. The CAD was defined as SDS ≥2. Chronic kidney disease (CKD) was defined as eGFR
Databáze: OpenAIRE
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