Simian varicella virus antibody response in experimental infection of African green monkeys
| Autor: | Nanette J. Gusick, Wayne L. Gray, Thomas M. Fletcher, Kenneth F. Soike |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Herpesvirus 3
Human Time Factors viruses Herpesvirus 1 Cercopithecine Biology Simian medicine.disease_cause Antibodies Viral Neutralization Simian varicella virus Immune system Chickenpox Immunity Neutralization Tests Chlorocebus aethiops medicine Animals Humans Viremia Antigens Viral Vero Cells integumentary system General Veterinary Antibody titer Varicella zoster virus virus diseases Herpesviridae Infections biochemical phenomena metabolism and nutrition biology.organism_classification Virology Anorexia Immunology Antibody Formation Animal Science and Zoology African Green Monkey |
| Zdroj: | Journal of medical primatology. 24(4) |
| ISSN: | 0047-2565 |
| Popis: | The humoral immune response to simian varicella virus (SVV) was investigated following primary and secondary experimental infection of African green monkeys. Neutralization and immunoprecipitation assays were used to determine antibody titers to SVV throughout the course of infection. The immune response to specific viral polypeptides was analyzed by immunoprecipitation analysis. The results demonstrate that the simian varicella model offers a useful approach to investigate immune mechanisms in human varicella zoster virus (VZV) infections. |
| Databáze: | OpenAIRE |
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