Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study
Autor: | Nicole Rosa de Freitas, Ana Lúcia Pompéia Fraga de Almeida, Simone Soares, L. B. Guerrini, Gisele da Silva Dalben, Michyele Cristhiane Sbrana, Luis Augusto Esper |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_specialty Critical size defect Urology Calvaria Bone healing LASER NÃO CIRÚRGICO Random Allocation 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Osteogenesis Reference Values In vivo Male rats Autograft medicine Animals Low-Level Light Therapy Rats Wistar Autogenous bone Autografts Bone regeneration General Dentistry Wound Healing Guided Tissue Regeneration business.industry Lasers Skull Significant difference Reproducibility of Results 030206 dentistry lcsh:RK1-715 Treatment Outcome medicine.anatomical_structure lcsh:Dentistry Original Article Collagen business |
Zdroj: | Journal of Applied Oral Science v.26 2018 Journal of applied oral science Universidade de São Paulo (USP) instacron:USP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Journal of Applied Oral Science, Vol 26, Iss 0 (2018) Journal of Applied Oral Science, Volume: 26, Article number: e20170244, Published: 07 MAY 2018 Journal of Applied Oral Science |
Popis: | The repair of bone defects raises the interest of investigators in several health specialties. Grafting techniques with bone substitutes and laser therapies have been investigated to replace autogenous bone and accelerate the bone healing process. Objective To evaluate the effect of photobiomodulation therapy (PBMT) associated with guided bone regeneration (GBR) in critical size defects. Material and Methods The study was conducted on 80 male rats (Rattus norvegicus albinus, Wistar) submitted to surgical creation of a critical size defect on the calvaria, divided into eight study groups: group C (control - only blood clot); group M (collagen membrane); group PBMT (photobiomodulation therapy); group AB (autogenous bone); group AB+PBMT; group AB+M; group PBMT+M; group AB+PBMT+M. The animals were killed 30 days postoperatively. After tissue processing, bone regeneration was evaluated by histomorphometric analysis and statistical analyses were performed (Tukey test, p |
Databáze: | OpenAIRE |
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