Male–female differences in quality of life and coping style in patients with Marfan syndrome and hereditary thoracic aortic diseases
| Autor: | Arjen L. Gökalp, Carlijn G.E. Thijssen, Johanna J.M. Takkenberg, Laura H. C. Elbers‐van de Ven, Niels van Royen, Roland R.J. van Kimmenade, Jolien W. Roos-Hesselink, Jeannette B. Peters, Janneke Timmermans, Daphne E. Doze |
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| Přispěvatelé: | Cardiology, Cardiothoracic Surgery |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male psychosocial medicine.medical_specialty Coping (psychology) Genetic counseling Population Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] Aortic Diseases Disease Hospital Anxiety and Depression Scale Marfan Syndrome Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] Sex Factors Surveys and Questionnaires Internal medicine Adaptation Psychological medicine Humans sex Outpatient clinic education Genetics (clinical) education.field_of_study genetic counseling health‐related quality of life business.industry distress Vascular damage Radboud Institute for Molecular Life Sciences [Radboudumc 16] Original Articles Middle Aged Distress Mental Health Quality of Life Female Original Article business Psychosocial |
| Zdroj: | Journal of Genetic Counseling, 29, 1259-69 Journal of Genetic Counseling, 29(6), 1259-1269. Human Sciences Press/Kluwer Academic Journal of Genetic Counseling, 29, 6, pp. 1259-69 Journal of Genetic Counseling |
| ISSN: | 1573-3599 1059-7700 |
| Popis: | Contains fulltext : 229890.pdf (Publisher’s version ) (Open Access) Hereditary thoracic aortic diseases (HTAD) such as Marfan syndrome (MFS) affect multiple organ systems and provide a risk of acute aortic dissection, which causes lifelong uncertainties. Although health‐related quality of life (HRQOL) was found to be reduced in HTAD patients, no studies have evaluated male–female‐specific aspects of HRQOL and coping in this population. This study aims to evaluate HRQOL in HTAD patients compared to the general population; assess male–female differences in HRQOL and factors associated with HRQOL; evaluate coping styles in male and female HTAD patients and identify factors associated with acceptance. All consecutive adult patients who visited the specialized HTAD outpatient clinic between 2013 and 2018 were asked to complete three HRQOL questionnaires: the Short Form 36 (SF‐36), the Hospital Anxiety and Depression Scale (HADS), and the Nijmegen Clinical Screening Instrument (NCSI). In total, 142 patients were included (mean age 42.1 years, 65 females, 123 MFS). Compared to the general population, HTAD patients scored significantly lower on multiple SF‐36 sub‐domains (males: General Health 54.5 ± 18.8 vs. 71.6 ± 20.6, p |
| Databáze: | OpenAIRE |
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