The role of the circadian system in the etiology and pathophysiology of ADHD

Autor: J. J. Sandra Kooij, Madelon A. Vollebregt, Denise Bijlenga, Martijn Arns
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Light therapy
DEFICIT HYPERACTIVITY DISORDER
medicine.medical_treatment
SUBSEQUENT RECOVERY
Delayed sleep phase
behavioral disciplines and activities
03 medical and health sciences
0302 clinical medicine
Attention Deficit Disorder with Hyperactivity/complications
Sleep Disorders
Circadian Rhythm
Sleep Initiation and Maintenance Disorders
mental disorders
medicine
Attention deficit hyperactivity disorder
Humans
ADHD
0501 psychology and cognitive sciences
Sleep Hygiene
Sleep restriction
Chronotherapy
LIGHT THERAPY
Sleep disorder
Sleep hygiene
Delayed sleep
Sleep-onset insomnia
GEOGRAPHIC-VARIATION
Circadian rhythm
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER
05 social sciences
Chronotherapy (sleep phase)
CONVERGENCE INSUFFICIENCY
General Medicine
Sleep disorders
SCHOOL-AGE-CHILDREN
medicine.disease
Sleep Initiation and Maintenance Disorders/complications
Psychiatry and Mental health
Clinical Psychology
MORNINGNESS-EVENINGNESS PREFERENCE
Sensorimotor rhythm
CLOCK GENE
SLEEP RESTRICTION
Attention Deficit Disorder with Hyperactivity
Circadian Rhythm/complications
Psychology
030217 neurology & neurosurgery
050104 developmental & child psychology
Clinical psychology
Zdroj: Bijlenga, D, Vollebregt, M A, Kooij, J J S & Arns, M 2019, ' The role of the circadian system in the etiology and pathophysiology of ADHD: time to redefine ADHD? ', ADHD Attention Deficit and Hyperactivity Disorders, vol. 11, no. 1, pp. 5-19 . https://doi.org/10.1007/s12402-018-0271-z
ISSN: 1866-6116
DOI: 10.1007/s12402-018-0271-z
Popis: Attention-deficit/hyperactivity disorder (ADHD) is highly associated with the delayed sleep phase disorder, a circadian rhythm sleep–wake disorder, which is prevalent in 73–78% of children and adults with ADHD. Besides the delayed sleep phase disorder, various other sleep disorders accompany ADHD, both in children and in adults. ADHD is either the cause or the consequence of sleep disturbances, or they may have a shared etiological and genetic background. In this review, we present an overview of the current knowledge on the relationship between the circadian rhythm, sleep disorders, and ADHD. We also discuss the various pathways explaining the connection between ADHD symptoms and delayed sleep, ranging from genetics, behavioral aspects, daylight exposure, to the functioning of the eye. The treatment options discussed are focused on improvement of sleep quality, quantity, and phase-resetting, by means of improving sleep hygiene, chronotherapy, treatment of specific sleep disorders, and by strengthening certain neuronal networks involved in sleep, e.g., by sensorimotor rhythm neurofeedback. Ultimately, the main question is addressed: whether ADHD needs to be redefined. We propose a novel view on ADHD, where a part of the ADHD symptoms are the result of chronic sleep disorders, with most evidence for the delayed circadian rhythm as the underlying mechanism. This substantial subgroup should receive treatment of the sleep disorder in addition to ADHD symptom treatment.
Databáze: OpenAIRE
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