In vitro and in silico studies of fluorinated 2,3-disubstituted thiazolidinone-pyrazoles as potential α-amylase inhibitors and antioxidant agents

Autor:	Devaraj Ganavi, Ramith Ramu, Vasantha Kumar, Shashank M. Patil, Reshma M. Martiz, Prithvi S. Shirahatti, Reshma Sathyanarayana, Boja Poojary, B. Shivarama Holla, Vishwanatha Poojary, K. P. Nanda Kumari, Jagadeep Chandra Shivachandra
Rok vydání:	2021
Předmět:	Molecular Docking Simulation Structure-Activity Relationship Drug Discovery Pharmaceutical Science Pyrazoles Glycoside Hydrolase Inhibitors alpha-Amylases Antioxidants
Zdroj:	Archiv der PharmazieREFERENCES. 355(3)
ISSN:	1521-4184
Popis:	As part of our effort to identify potent α-amylase inhibitors, in the present study, a novel series of fluorinated thiazolidinone-pyrazole hybrid molecules were prepared by the condensation of 3-(aryl/benzyloxyaryl)-pyrazole-4-carbaldehydes with fluorinated 2,3-disubstituted thiazolidin-4-ones. The structures of the newly synthesized compounds were confirmed by infrared
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8edcdbc740c1a959babc01b8350dc4 https://pubmed.ncbi.nlm.nih.gov/34923670 Zobrazit plný text záznamu Plný text