JAK Inhibitors for the Treatment of Pediatric Alopecia Areata
| Autor: | Brittany G. Craiglow, Claire E. Hamilton |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Adolescent Alopecia Areata Administration Oral Dermatology Administration Cutaneous Piperidines Quality of life Neoplasms Nitriles medicine Humans Janus Kinase Inhibitors Child skin and connective tissue diseases Molecular Biology integumentary system Extramural business.industry Alopecia totalis Cell Biology General Medicine Alopecia areata medicine.disease Arthritis Juvenile Pyrimidines Child Preschool Alopecia universalis Pyrazoles Autoimmune condition business Biotechnology |
| Zdroj: | Journal of Investigative Dermatology Symposium Proceedings. 20:S31-S36 |
| ISSN: | 1087-0024 |
| DOI: | 10.1016/j.jisp.2020.04.005 |
| Popis: | Alopecia areata is a common autoimmune condition that disproportionately affects children and can significantly hinder quality of life. Few safe and effective therapies are available for the treatment of severely affected pediatric patients. JAK inhibitors have been recently established as an effective and well-tolerated therapy in adults, but there are limited data regarding the use of JAK inhibitors to treat alopecia areata in children. Here, we review the available literature regarding the use of JAK inhibitors in children in dermatology and across other medical disciplines. |
| Databáze: | OpenAIRE |
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