Pharmacological interventions for painful diabetic neuropathy: Comparative analysis using network meta‐analysis
| Autor: | Hitoshi Yasuda |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Diabetic neuropathy business.industry Endocrinology Diabetes and Metabolism General Medicine medicine.disease Surgery Peripheral neuropathy Quality of life Commentaries Meta-analysis Diabetes mellitus Neuropathic pain Internal Medicine Medicine business Intensive care medicine Polyneuropathy Glycemic |
| Zdroj: | Journal of Diabetes Investigation |
| ISSN: | 2040-1124 2040-1116 |
| DOI: | 10.1111/jdi.12354 |
| Popis: | Diabetic peripheral neuropathy is a common complication of diabetes mellitus that disturbs the quality of life of affected persons. Although diabetic neuropathy includes many types of different pathogeneses and clinical manifestations, the most common type is chronic sensorimotor distal symmetrical polyneuropathy. Among a variety of symptoms as a result of this type of neuropathy, neuropathic pain must be one of the most devastating problems. When painful symptoms are predominant, it is often called ‘painful diabetic neuropathy’ (PDN). It is well known that functionality and quality of life have been deeply disturbed in patients with PDN. Therefore, the therapeutic strategy should be directed toward satisfactory relief of pain symptoms. The first therapeutic step for PDN should be glycemic control. However, patients occasionally require analgesics, even despite glycemic normalization. In addition, the best approach for pain control must be ‘the sooner, the better’ approach. Thus, development of beneficial analgesics are essential. At the present time, several classes of analgesics are available for treating PDN. |
| Databáze: | OpenAIRE |
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