Hypopharyngeal cancer associated with synchronous oesophageal cancer: risk factors and benefits of image-enhanced endoscopic screening
| Autor: | G Q Wang, Xin-Hai Ni, Qing-Qing Zhang, Ji-Qing Zhu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Esophageal Neoplasms Laryngoscopy Gastroenterology Chromoendoscopy Neoplasms Multiple Primary 03 medical and health sciences Narrow Band Imaging 0302 clinical medicine Risk Factors Internal medicine medicine Humans 030223 otorhinolaryngology Aged Retrospective Studies Aged 80 and over Hypopharyngeal Neoplasms medicine.diagnostic_test business.industry Carcinoma Cancer Hypopharyngeal cancer General Medicine Odds ratio Second primary cancer Esophageal cancer Middle Aged medicine.disease Image Enhancement Otorhinolaryngology 030220 oncology & carcinogenesis Female Endoscopic screening Esophagoscopy business |
| Zdroj: | The Journal of laryngology and otology. 132(2) |
| ISSN: | 1748-5460 0022-2151 |
| Popis: | Objectives:To explore the risk factors associated with the occurrence of synchronous oesophageal cancer in patients with hypopharyngeal cancer, and to investigate the roles of image-enhanced endoscopic screening in the prediction and diagnosis of early oesophageal cancer.Methods:The clinical characteristics of patients with hypopharyngeal cancer (n = 160) were analysed. All patients underwent laryngoscopic and gastroscopic examination using image-enhanced endoscopic techniques before treatment.Results:Of 160 hypopharyngeal cancer patients, 43 (27 per cent) had synchronous oesophageal cancer. Heavy drinking (odds ratio = 4.787, p = 0.029) and local invasion of three or more anatomical sites (odds ratio = 14.391, p = 0.000) were independent risk factors for synchronous oesophageal cancer. Narrow-band imaging laryngoscopy could detect more invaded anatomical sites than ordinary white light endoscopy (t = 8.532, p = 0.000). More early oesophageal cancer cases were detected with Lugol chromoendoscopy than with non-Lugol iodine staining examination (χ2 = 4.925, p = 0.026).Conclusion:Synchronous oesophageal cancer is common in patients with hypopharyngeal cancer. The heavy drinking patients with hypopharyngeal cancer should undergo intensive monitoring. Image-enhanced endoscopic screening is helpful in the prediction and early detection of second primary oesophageal cancer. |
| Databáze: | OpenAIRE |
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