Endoscopic Ultrasonography-guided Fine-needle Aspiration Cytology Combined with a Cell-block Method for Gastrointestinal Subepithelial Lesions
| Autor: | Hiroaki Kusunose, Tetsuya Ohira, Yutaka Noda, Shinsuke Koshita, Yoshihide Kanno, Taku Yamagata, Yoshihiro Harada, Toshitaka Sakai, Kei Ito, Takeshi Shimizu, Masaya Oikawa, Takashi Tsuchiya, Takashi Sawai, Takahisa Ogawa |
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| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
Gastrointestinal Stromal Tumors Concordance medicine.medical_treatment Endoscopic ultrasonography Endosonography Fine needle aspiration cytology Biopsy Internal Medicine medicine Humans Stromal tumor skin and connective tissue diseases Endoscopic Ultrasound-Guided Fine Needle Aspiration neoplasms Retrospective Studies Chemotherapy GiST medicine.diagnostic_test business.industry Histology General Medicine body regions surgical procedures operative Radiology business |
| Zdroj: | Internal Medicine. 61:935-942 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.7889-21 |
| Popis: | Introduction The diagnostic accuracy of an endoscopic ultrasound-guided fine-needle aspiration cytology/biopsy combined with a cell-block method (FNA-CB) for gastrointestinal subepithelial lesions (GI-SELs) has not been fully studied. Methods A total of 109 patients (with 110 GI-SELs) were evaluated to clarify the rate of obtaining evaluable histology specimens using FNA-CB. In addition, we investigated the following: 1) the accuracy for determining the histology, 2) effects of the number of cell clusters obtained via FNA-CB, 3) correlation of the Ki67 labelling index (Ki67LI) of the gastrointestinal stromal tumor (GIST) lesions between FNA-CB and resected specimens, and 4) clinical courses for patients followed up after FNA-CB. Results Of the 110 GI-SELs for which FNA-CB was performed, 95 (86%) were able to be histologically evaluated using the first FNA-CB. For the 70 resected GI-SELs, the accuracy of FNA-CB to determine histology was 96%, remaining at 90% even when only a few cell clusters were obtained. The concordance rate of the risk-grouping of GIST (high-risk, Ki67LI ≥8; low-risk |
| Databáze: | OpenAIRE |
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