Relation of C-reactive protein to extent and complexity of coronary narrowing in patients with non-ST elevation acute coronary syndromes. A prospective cohort study
| Autor: | Jose M. Gabay, Alejandro Tettamanzi, Jorge Mrad, Ricardo Sarmiento, Jose Alvarez, Raul De Miguel, Carlos Rapallo, Luis A. Guzman, Fernando Botto, José Luis Navarro Estrada, Carlos Rojas Matas, Alfredo Hirschson-Prado, Carlos Sztejfman, Alejandra Farras |
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| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Coronary Angiography Cohort Studies Coronary artery disease Troponin T Predictive Value of Tests Internal medicine medicine Humans Prospective Studies Myocardial infarction Prospective cohort study Aged Inflammation biology business.industry ST elevation C-reactive protein Coronary Stenosis General Medicine Middle Aged medicine.disease C-Reactive Protein Treatment Outcome Cohort biology.protein Cardiology Female Cardiology and Cardiovascular Medicine business Biomarkers TIMI Cohort study |
| Zdroj: | Coronary Artery Disease. 15:477-484 |
| ISSN: | 0954-6928 |
| DOI: | 10.1097/00019501-200412000-00004 |
| Popis: | BACKGROUND Inflammatory markers have been associated with adverse clinical outcome in patients with acute coronary syndromes (ACS). In addition, angiographic plaque morphology and extension of coronary artery disease has been related to worse prognosis in this group of patients. The aim of the present study was to determine if the clinical prognostic value of C-reactive protein (CRP), an inflammatory marker, can by associated with the angiographic findings in patients with non-ST elevation ACS. METHODS This prospective multicenter cohort study included 1253 patients with non-ST elevation ACS. CRP, which was considered positive (+) if >/=3 mg/l, was measured at a median of 9 h from symptoms onset and were kept blinded until the end of the study. Coronary angiography was performed in 633 patients (50%). The presence of complex coronary lesions (CCLs) was defined as the presence of any of the following: thrombus (+), Thrombolysis In Myocardial Infarction (TIMI) flow |
| Databáze: | OpenAIRE |
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