Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy

Autor: Audrey Souverain, Susanne Hartwig, Vincenzo Baldo, Céline Ballandras, Nadia Raccanello, Marco Villa, Rebecca Lundin, Giovanni Gabutti, Carlo Giaquinto, Lara Tramontan, Stéphane Thomas, Xavier Cornen, Emilia Perinetti, Chiara Poma, Antonio Scamarcia, Francesca Russo, Luigi Cantarutti
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: BMC Infectious Diseases
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-9 (2018)
ISSN: 1471-2334
Popis: Background Monovalent varicella vaccines have been available in the Veneto Region of Italy since 2004. In 2006, a single vaccine dose was added to the immunisation calendar for children aged 14 months. ProQuad®, a quadrivalent measles-mumps-rubella-varicella vaccine, was introduced in May 2007 and used, among other varicella vaccines, until October 2008. This study aimed to evaluate the effectiveness of a single dose of ProQuad, and the population impact of a vaccination program (VP) against varicella of any severity in children who received a first dose of ProQuad at 14 months of age in the Veneto Region, Methods All children born in 2006/2007, i.e., eligible for varicella vaccination after ProQuad was introduced, were retrospectively followed through individual-level data linkage between the Pedianet database (varicella cases) and the Regional Immunization Database (vaccination status). The direct effectiveness of ProQuad was estimated as the incidence rate of varicella in ProQuad-vaccinated children aged
Databáze: OpenAIRE
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