Hepatitis B and C virus infection among 1.2 million persons with access to care: factors associated with testing and infection prevalence
| Autor: | Philip R, Spradling, Loralee, Rupp, Anne C, Moorman, Mei, Lu, Eyasu H, Teshale, Stuart C, Gordon, Cynthia, Nakasato, Joseph A, Boscarino, Emily M, Henkle, David R, Nerenz, Maxine M, Denniston, Scott D, Holmberg, Erin M, Keast |
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| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty National Health and Nutrition Examination Survey Hepatitis C virus Population medicine.disease_cause Article Internal medicine Odds Ratio Prevalence Medicine Humans education Aged Retrospective Studies Hepatitis B virus Aged 80 and over education.field_of_study business.industry Odds ratio Hepatitis C Hepatitis B Middle Aged medicine.disease digestive system diseases United States Infectious Diseases Immunology Multivariate Analysis Female business Viral hepatitis |
| Zdroj: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 55(8) |
| ISSN: | 1537-6591 |
| Popis: | Background. Little is known about viral hepatitis testing and infection prevalence among persons in private healthcare organizations (HCOs) in the United States. Methods. To determine the frequency of and characteristics associated with viral hepatitis testing and infection prevalence among adults with access to care, we conducted an observational cohort study among 1.25 million adults from 4 US HCOs and included persons with ≥1 clinical encounter during 2006–2008 and ≥12 months of continuous follow-up before 2009. We compared the number of infections identified with the number expected based on adjusted data from the National Health and Nutrition Examination Survey (NHANES). Results. Of 866 886 persons without a previous hepatitis B virus (HBV) diagnosis, 18.8% were tested for HBV infection, of whom 1.4% tested positive; among 865 659 without a previous hepatitis C virus (HCV) diagnosis, 12.7% were tested, of whom 5.5% tested positive. Less than half of those with ≥2 abnormal alanine aminotransferase (ALT) levels were subsequently tested for HBV or HCV. When tested, Asians (adjusted odds ratio [aOR] 6.33 relative to whites) were most likely HBV infected, whereas those aged 50–59 years were most likely HCV infected (aOR 6.04, relative to age |
| Databáze: | OpenAIRE |
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